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||Welcome to AnticoagulationWeb.com,
The Anticoagulation Information Source, an Internet site designed for
physicians and other health care personnel who want information about
anticoagulation, coagulation, and therapeutic perspectives in anticoagulation
therapy. Anticoagulation therapy is used for the treatment and prevention
of a variety of thromboembolic disorders, but is also used for therapeutic
applications including extracorporeal circulation, cardiopulmonary bypass,
and surgical and other procedures including cardiac catheterization and
percutaneous interventions. Heparin and its derivatives are the most widely
used pharmacologic agents for these purposes. Heparin is also used
|for the initial treatment of venous thromboembolism,
acute coronary syndromes including myocardial infarction, and hemodialysis.
The development of low molecular weight heparins (LMWHs) has simplified
the prevention and treatment of thrombotic disorders because these agents
are administered by subcutaneous injection once or twice daily without laboratory
monitoring. Other types of antithrombotic and anticoagulant treatment have
become available or are under clinical development, including antiplatelet
drugs, snake venoms, direct and indirect thrombin inhibitors, activated
protein C, antithrombin III, recombinant hirudin, and bivalirudin as examples.
Because of the pivotal role of anticoagulation in cardiovascular disease,
surgery, critical care, trauma, perioperative medicine, and hematology,
therapeutic approaches to anticoagulation are important. Further a broad
spectrum of novel anticoagulants have assumed a pivotal role in clinical
medicine, yet at the same time present the potential for bleeding. This
site provides links to the resources available regarding these important
issues on the Internet.
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